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在催化量的铜存在下,氟烷基碘R_FI(1)与乙烯基三甲基硅烷(2)在乙腈中反应生成高产率的氟烷基化产物8,二碘化物I(CF_2)_nI(4)也能与2反应生成单烷基化产物5和双烷基化产物6,5和6量的相对比例取决于所用2的量.这类反应能被对苯二酚阻止:被对二硝基苯部分阻止,碘苯未能捕获到氟烷基铜中间体.表明反应可能是单电子转移引发的自由基链式机理.3与二乙胺反应得高产率的反式氟烷基三甲基硅乙烯7.3与氢氧化钾在乙醇中反应得到的是7及其顺式异构体的混合物,将混合物用少量的溴处理可得纯的反式烯烃.
The fluoroalkyl iodides R_FI (1) reacted with vinyltrimethylsilane (2) in acetonitrile in the presence of a catalytic amount of copper to yield the fluoroalkylated product 8, the diiodide I (CF_2) _nI 4) The relative proportions that can also be reacted with 2 to form the monoalkylated product 5 and the di-alkylated products 6, 5 and 6 depend on the amount used 2. Such reactions can be stopped by hydroquinone: Nitrobenzene partially blocked iodine benzene failed to capture the fluoroalkyl copper intermediates, indicating that the reaction may be caused by the single electron transfer free radical chain mechanism.3 The reaction with diethylamine yield high yield of trans-fluoroalkyl tris The reaction of methylvinylsulfone 7.3 with potassium hydroxide in ethanol yields a mixture of 7 and its cis-isomer. The mixture is treated with a small amount of bromine to yield pure trans-olefin.