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目的:研究舒乐冲剂对大鼠输卵管炎性阻塞模型的影响。方法:60只Wistar雌性大鼠分为:空白对照组、阳性药对照组、模型组、舒乐冲剂高、中、低剂量组。子宫注入20%苯酚糊剂0.01ml诱发大鼠输卵管炎性阻塞性不孕实验模型。分别连续灌胃给药30d后取血进行药效学的血液流变学检测,取子宫肉眼观察。结果:舒乐冲剂可显著改善造模大鼠输卵管通畅情况、降低输卵管炎症程度及改善血液流变学指标。结论:舒乐冲剂对大鼠输卵管炎性阻塞模型有治疗作用。
Objective: To study the effect of Shule Granules on the oviductal occlusion model in rats. Methods: Sixty female Wistar rats were divided into blank control group, positive drug control group, model group, Shule Granule high, middle and low dose groups. Intrauterine injection of 20% phenol paste 0.01ml induced rat tubal inflammatory obstructive infertility experimental model. After 30 days of continuous gavage administration, blood was taken for pharmacodynamic hemorheological examination and visually observed with the uterus. Results: Shule granules can significantly improve the patency of the fallopian tubes of model rats, reduce the degree of inflammation of the fallopian tubes, and improve the hemorheological parameters. Conclusion: Shule granules have therapeutic effects on rat oviduct inflammatory obstruction model.