中国药典1985年版二部620页醋酸地塞米松(醋酸氟美松)中硒(Se)的限量检查,方法为“取本品0.2g,依法测定(附录36页),含硒量不得过百万分之五十”。我们在测定中,认为该法有以下两个问题。 1.附录中硒标准液浓度为每1ml相当于1μg的Se,硒对照液制备时精密吸取硒标准液5ml,即相当于5μg的Se。附录又规定,供试品溶液的吸收度不得大于硒对照液的吸收度,这样,根据醋酸地塞米松取 Chinese Pharmacopoeia 1985 edition two 620 620 dexamethasone acetate (dexamethasone acetate) in the selenium (Se) limit check method for “take this product 0.2g, according to the determination (Appendix 36), the amount of selenium must not Fifty thousandths of an inch. ” In our test, we think the law has the following two problems. 1. Appendix selenium standard solution concentration per 1ml equivalent to 1μg of Se, selenium control solution preparation precision selenium standard solution 5ml, which is equivalent to 5μg of Se. Appendix also provides for the absorption of the test solution shall not be greater than the absorption of selenium control solution, so, according to dexamethasone acetate take