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目的:观察四物汤传统饮片汤剂与配方颗粒汤剂对血虚小鼠外周血细胞的影响,比较两者改善外周血象的效果。方法:分别用四物汤传统饮片汤剂与配方颗粒汤剂对急性大量失血引起的失血性模型及联合注射乙酰苯肼和环磷酰胺引起的化学损伤性血虚症小鼠模型灌胃处理后观察外周血细胞的变化。结果:四物汤配方颗粒汤剂与传统饮片汤剂不同剂量组均有不同程度升高外周血细胞的作用,两者无显著性统计学差异。结论:四物汤配方颗粒汤剂与传统饮片汤剂均具有明显的补血作用,2种剂型效果基本相当。
OBJECTIVE: To observe the effects of Siwutang Traditional Decoction Decoction and formula granule decoction on peripheral blood cells in blood deficiency mice and to compare the effects of the two methods in improving peripheral blood. Methods: After the administration of Siwutang Traditional Decoction Decoction and Formula granule decoction respectively, the hemorrhagic model induced by acute massive blood loss and the combined administration of acetophenone and cyclophosphamide-induced chemical injury blood deficiency model mice were observed after intragastric administration. Changes in peripheral blood cells. Results: Siwutang recipe granule decoction and traditional decoction decoction in different dosage groups all increased the peripheral blood cells in different degrees, and there was no statistically significant difference between the two groups. Conclusion: Siwutang prescription granule decoction and traditional decoction decoction both have obvious blood-supplementing effect, and the effect of two dosage forms is basically the same.