目的 :探讨机关干部高尿酸血症的患病情况及与性别、年龄的关系。方法 :对健康体检的 6 78名机关干部的血尿酸、血糖、血脂及肝肾功能进行分析。结果 :高尿酸血症检出率为 14 0 1% ,其中 ,男性 2 1 4 4 % ,女性 4 12 % ,两者比较有显著性差异 (P <0 0 5 )。高尿酸血症患病率随年龄增长而上升 ,5 0～ 70岁为高发年龄段 ,而且多伴有血糖、甘油三酯、低密度脂蛋白及载脂蛋白B增高。结论 :高尿酸血症存在性别与年龄差别 ,是发生代谢综合症的重要危险因素 ,应当引起人们高度重视 Objective: To investigate the prevalence of hyperuricemia and its relationship with gender and age in cadres. Methods: The blood uric acid, blood glucose, blood lipid and liver and kidney function of 6 78 cadres in health examination were analyzed. Results: The detection rate of hyperuricemia was 14 0 1%, of which, 2 14.4% were male and 4 12% were female, showing significant difference (P <0.05). The prevalence of hyperuricemia increased with age. The prevalence of hyperuricemia increased from 50 to 70 years of age and was accompanied by increased blood sugar, triglycerides, low density lipoprotein and apolipoprotein B levels. Conclusions: The difference of sex and age of hyperuricemia is an important risk factor of metabolic syndrome and should be paid great attention