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据认为因胃肠道局部内脏感觉改变所致的症状是功能性肠病的一个重要发病机制。然而,患有某种胃肠功能性症状的病人常伴有胃肠道其他部位的症状,提示内脏感觉的增强可能是一种全胃肠道的现象。作者测定了12例肠易激综合征(IBS)和10例功能性消化不良(FD)患者在球囊扩张直肠时的初始感觉(IP)、便意(DD)和紧迫感(U)的阈值以及球囊扩张食管时的初始感觉和不适感的阈值,另测定了他们的躯体感觉阈值,并与正常人进行了比较。 结果:12例IBS患者中3例有上消化道症状,10例FD患者中4例有与结肠相关的症
It is thought that the symptoms caused by the change of visceral local visceral gastrointestinal tract are an important pathogenesis of functional bowel disease. However, patients with some gastrointestinal symptoms are often accompanied by symptoms of other parts of the gastrointestinal tract, suggesting that increased visceral sensation may be a pan-gastrointestinal phenomenon. The authors measured the threshold values for initial sensation (IP), convenience (DD), and urgency (U) for the balloon dilatation of the rectum in 12 patients with irritable bowel syndrome (IBS) and 10 patients with functional dyspepsia Thresholds of initial sensory and discomfort during balloon dilatation of the esophagus, and their somatosensory thresholds were also measured and compared to normal subjects. RESULTS: Three of 12 IBS patients had upper gastrointestinal symptoms and 4 of 10 FD patients had colon-related disease