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铋盐制剂用来治疗胃肠疾病已有40多年的历史,近年来迪乐(De-Nol)冲剂(胶态次枸橼酸铋)治疗胃十二指肠溃疡、慢性浅表性胃炎、慢性萎缩性胃炎取得一定效果。胶态铋可杀灭幽门螺杆菌,可以降低溃疡病的复发率,提高治愈率,所以迪乐是目前治疗与幽门螺杆菌(HP)有关的胃十二指肠疾病的新一代胃粘膜保护药,是一种安全而理想的药物。我院于1989年11月开始应用湖北黄石市长征制药厂生产的De-Nol冲剂治疗胃及十二指肠疾病,并与雷尼替丁进行比较,观察De-Nol冲剂对HP的抗菌效果和对胃及十二指肠疾病的疗效。
Bismuth salt preparations have been used to treat gastrointestinal diseases for more than 40 years. In recent years, De-Nol granules (colloidal bismuth sub-citrate) have been used to treat gastroduodenal ulcer, chronic superficial gastritis, chronic Atrophic gastritis achieved some effect. Colloidal bismuth can kill Helicobacter pylori, can reduce the recurrence rate of ulcer disease and improve the cure rate, so Di music is the current treatment of Helicobacter pylori (HP) -related gastroduodenal disease, a new generation of gastric mucosal protective drugs , Is a safe and ideal medicine. In November 1989, our hospital began to apply De-Nol granule produced by Changzheng Pharmaceutical Factory in Huangshi City, Hubei Province for the treatment of gastric and duodenal diseases and compared with ranitidine to observe the antibacterial effect of De-Nol granules on HP and Efficacy on gastric and duodenal diseases.