论文部分内容阅读
目的对2010年11月～2011年11月15 069例孕中期孕妇在湖北省妇幼保健院参加产前筛查的结果进行回顾分析。方法用电化学发光法检测孕中期(14-20周)孕妇血清中的三项指标(AFP、T-βHCG、uE3),并结合孕妇年龄,孕周,体重等因素,再通过专用软件计算唐氏征的风险度。结果筛查15 069例孕妇有1105例筛查呈阳性,在自愿接受羊水检查的孕妇中,检出唐氏征胎儿10例,18-三体综合征3例,其他异常染色体胎儿6例。结论电化学发光法检测孕中期血清三联产前筛查是安全有效的产前筛查方法,可以有效地降低缺陷儿的出生率。
Objective To review the results of prenatal screening of 15 069 pregnant women in November 2010 ~ November 2011 in Hubei Maternal and Child Health Hospital. Methods The levels of AFP, T-βHCG and uE3 in serum of pregnant women during the second trimester (14-20 weeks) were detected by electrochemiluminescence. Based on the factors of pregnant women ’s age, gestational age, body weight and so on, The risk of the sign. Results Screening of 15 069 pregnant women, 1105 pregnant women were screened positive. Among the pregnant women who voluntarily received amniotic fluid examination, 10 fetuses with Down’s syndrome, 3 with 18-trisomy syndrome and 6 with other abnormal chromosomes were detected. Conclusion Electrochemiluminescence detection of trimester trimester serum screening is a safe and effective prenatal screening method that can effectively reduce the birth rate of defective children.