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现代的抗癌化疗药物可对机体造成许多不良影响。为评估结肠癌患者行FOLFOX-4和CLF-1方案化疗的毒性并进行两方案间的比较,Wiela-Hojeńska等纳入了64例结肠癌患者,其中行FOLFOX-4方案化疗48例,行CLF-1方案化疗16例。结果显示:两类化疗方案常见的不良反应为恶心、呕吐及神经毒性;接受FOLFOX-4方案化疗的患者,随着化疗周期的增加,其
Modern anti-cancer chemotherapeutic drugs can cause many adverse effects on the body. To assess the toxicity of chemotherapy with FOLFOX-4 and CLF-1 regimens in patients with colon cancer and to compare the two regimens, Wiela-Hojeńska et al. Enrolled 64 patients with colon cancer, including 48 FOLFOX-4 regimens and CLF- 1 chemotherapy in 16 cases. The results showed that: two kinds of chemotherapy regimens common adverse reactions are nausea, vomiting and neurotoxicity; patients receiving FOLFOX-4 chemotherapy, with the increase of chemotherapy cycles, its