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在8个健康人体研究了酮基布洛芬(KT)的对映异构体的药代动力学。口服单剂50mg和多剂每天三次,每次50mg连续3天给药,然后用立体专一性HPLC检查静脉血和尿中不同时间R-KT和S-KT的含量。发现在血浆中R-
The pharmacokinetics of the enantiomers of ketoprofen (KT) were studied in 8 healthy humans. Oral single dose of 50mg and multi-dose three times a day, each 50mg for 3 consecutive days of administration, and then three-dimensional specific HPLC examination of venous blood and urine at different times R-KT and S-KT content. Found in plasma R-