氨苯砜(DDS)于1947年开始用于治疗麻风病,1950年成功治愈疱疹样皮炎,以后临床上常单独或与其他药联合用于中性粒细胞介导等的皮肤病。近年来,其临床应用及制剂方面的研究取得了重大进展。现拟对DDS进行全面系统的介绍,为后续的研究提供必要的参考。 Dapsone (DDS) was used in the treatment of leprosy in 1947, herpes dermatitis was successfully treated in 1950, and then used clinically alone or in combination with other drugs for neutrophil-mediated skin diseases. In recent years, significant progress has been made in its clinical application and formulation research. It is proposed that a comprehensive and systematic introduction to DDS be provided for the follow-up study to provide the necessary reference.