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用传递函数法对左心导管测量的30例肺动脉压力资料进行福里哀分析,求出系统传递函数主极点所对应的交角频率。分析表明:肺动脉平均压与肺楔压之差和交角频率的倒数T_2之间,及肺动脉平均压和相应的交角频率的倒数T_1之间,均有很好的线性关系(r=0.898和0.810)。T_2,T_1的生理学意义分别相当于肺动脉和肺循环总时间常数与心动周期之比。由于时间常数可以用其他非损伤性方法近似测量,因而本文的结果可用于间接推算肺动脉平均压和肺动脉平均压与肺楔压之差。
The transfer function method was used to analyze the pulmonary artery pressure measured by left ventricular catheter in 30 patients with Forresse’s disease. The crossover frequency corresponding to the main pole of the system transfer function was obtained. The results showed that there was a good linear relationship (r = 0.898 and 0.810) between the mean pulmonary arterial pressure and pulmonary wedge pressure and the inverse T_2 of the crossover frequency, and between the average pulmonary artery pressure and the reciprocal T_1 of the corresponding crossover frequency. . The physiological significance of T_2 and T_1 are respectively the ratio of total time constant of pulmonary artery and pulmonary circulation to cardiac cycle. Since time constants can be approximated by other noninvasive methods, the results in this paper can be used to indirectly estimate the mean pulmonary artery pressure and the difference between pulmonary arterial pressure and pulmonary wedge pressure.