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大约15年前人们发现由T淋巴细胞释放的一种因子可调节B细胞的增殖和分化,使B细胞变成能分泌抗体的细胞。但其后人们了解到这种细胞因子并不是专一地作用于B细胞,它对其他多种靶细胞也有特殊的生物活性。不仅如此,除了T细胞,其他细胞也可分泌调节B细胞功能的因子。近年来研究细胞因子的报告越来越多,这些功能复杂的因子使命名和分类带来混乱,因此1986年在加拿大,多伦多召开的第六届国际免疫学会议上把已弄清其核苷酸序
About 15 years ago, it was discovered that a factor released by T lymphocytes can regulate the proliferation and differentiation of B cells and make B cells into cells capable of secreting antibodies. But then people learned that this cytokine does not specifically affect the B cells, it has a variety of other target cells have special biological activity. Not only that, other than T cells, other cells can also secrete factors that regulate B cell function. In recent years, more and more reports on cytokines have been reported. These complex functions cause confusion in terms of naming and classification. Therefore, at the 6th International Conference on Immunology held in Toronto, Canada in 1986,