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肝性脊髓病是慢性肝病晚期的一种特殊类型的并发症,较少见。1949年Leigh与Card首先报道。1957年Brown于尸检5例肝昏迷病人中,发现2例有脊髓侧索中度脱髓鞘。1960年Zieve等在肝硬化施行门脉-体循环吻合术后的1例患者,发现反复发作性脑症状及隐袭性进行性截瘫,尸检结果发现主要是脊髓锥体束的脱髓鞘病变,以后陆续有同样的报告。文献上称为肝硬化脊髓病、门腔脊髓病、分流性脑脊髓病等。
Hepatic myelopathy is a special type of complication of advanced liver disease, rare. 1949 Leigh and Card first reported. Brown in the autopsy in 5 cases of hepatic coma in 1957, found in 2 cases of moderate demyelination of the lateral spinal cord. In 1960, Zieve and other liver cirrhosis in the implementation of portal vein - a circulatory anastomosis in 1 patient and found recurrent brain symptoms and cryptogenic progressive paraplegia, autopsy findings mainly demyelinating spinal cord lesions, after One after another have the same report. Document known as cirrhosis of the spinal cord disease, the door cavity myelopathy, shunt cerebrospinal myopathy and so on.