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目的探讨非酒精性脂肪肝与心血管病危险因素的关系。方法随机选取体检人群6835例,根据肝脏B超检查结果分为非酒精性脂肪肝组(A组,3024例)和非脂肪肝组(B组,3811例),比较两组体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、甘油三酯(TG)和空腹血糖(FBG)水平。结果 18-59岁年龄段男性的非酒精性脂肪肝患病率高于女性(P<0.01)。A组BMI、SBP、DBP、TG、TC、LDL-C、FBG高于B组(P<0.01),A组HDL-C低于B组(P<0.01)。多因素Logistic回归分析显示,BMI、DBP、TG、HDL-C、FBG是非酒精性脂肪肝的危险因素。结论非酒精性脂肪肝与多种心血管病危险因素相关,应加强非酒精性脂肪肝心血管病危险因素的控制。
Objective To investigate the relationship between nonalcoholic fatty liver and cardiovascular risk factors. Methods Sixty-eight (6835) were randomly selected and divided into non-alcoholic fatty liver group (A group, 3024 cases) and non-fatty liver group (B group, 3811 cases) according to liver ultrasonography. The body mass index (BMI) SBP, DBP, HDL-C, LDL-C, TG, fasting blood glucose (FBG) (FBG) level. Results The prevalence of non-alcoholic fatty liver in 18-59-year-old men was higher than that in women (P <0.01). The serum levels of BMI, SBP, DBP, TG, TC, LDL-C and FBG in group A were higher than those in group B (P <0.01). HDL-C in group A was lower than that in group B (P <0.01). Multivariate logistic regression analysis showed that BMI, DBP, TG, HDL-C and FBG were risk factors of nonalcoholic fatty liver disease. Conclusion Non-alcoholic fatty liver disease is associated with a variety of risk factors of cardiovascular disease, and should be strengthened to control the risk factors of non-alcoholic fatty liver disease.