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人类各种疾病中血清总补体或单一成分含量可发生变化,因之补体水平测定或组织定位观察有助于对某些疾病发病机理的探讨。有关实验证实在实验性矽肺动物模型大鼠肺巨噬细胞表面 C_3受体增加并有促进吞噬功能的现象,且测定矽肺和煤矽肺病人外周血中补体 C_3含量有显著增高,但也有报导矽肺和煤矽肺病人血清补体 C_3水平变化不显或甚致下降。为此我们使用二种
Serum total complement or single component content of various human diseases can change, so the level of complement determination or tissue location observation is helpful to explore the pathogenesis of certain diseases. The experiment confirmed that the C_3 receptor on the surface of lung macrophages in experimental rat model of silicosis increased and promoted phagocytosis, and the content of complement C_3 in peripheral blood of patients with silicosis and coal silicosis was significantly increased. However, there were also reports of silicosis and Serum complement C_3 level in coal silicosis patients showed no significant change or even decreased. For this we use two kinds