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目的探讨百草枯中毒的救冶方法。方法回顾性分析2003年5月至2006年5月湖北省枣阳市第一人民医院收治的20例百草枯中毒患者。按治疗方法分为两组:血液灌流联合血液透析串联组10例(治疗组)和常规治疗组10例(对照组)。两组均采用洗胃、导泻及相关对症治疗。治疗组在基础治疗的同时,采用桡动脉及股静脉穿刺建立的临时血管通路行血液灌流联合血流透析,血流量保持在150 mL/min,每次治疗时间为2 h。结果治疗组10例患者痊愈6例,死亡4例。对照组10例患者痊愈2例,死亡8例。治疗组与对照组疗效差异有显著性意义。结论血液灌流联合血液透析串联救治百草枯中毒临床效果好,值得推广。
Objective To explore paraquat poisoning salvage method. Methods From May 2003 to May 2006, 20 cases of paraquat poisoning admitted to First People’s Hospital of Zaoyang City, Hubei Province were retrospectively analyzed. According to the method of treatment, the patients were divided into two groups: hemoperfusion combined with hemodialysis series group of 10 patients (treatment group) and conventional treatment group of 10 patients (control group). Two groups were used gastric lavage, catharsis and related symptomatic treatment. In the treatment group, hemoperfusion and hemodialysis were performed on the temporary vascular access established by radial artery and femoral vein puncture at the same time as the basic treatment. The blood flow was maintained at 150 mL / min, and the treatment time was 2 h. Results In the treatment group, 10 patients recovered 6 cases and 4 died. Control group, 10 patients recovered in 2 cases, 8 patients died. There was significant difference between the treatment group and the control group. Conclusion Hemoperfusion combined with hemodialysis tandem paraquat poisoning clinical effect is good, it is worth promoting.