论文部分内容阅读
目的:初步评价~(125)I放射性籽源植入术联合内分泌疗法治疗前列腺癌的临床疗效。方法:应用术中经直肠超声引导及治疗计划系统软件经会阴穿刺植入~(125)I放射性籽源并同期行手术去势或药物去势治疗前列腺癌患者29例。结果:术后6个月～5年随访,发现29例患者前列腺体积及前列腺特异抗原(PSA)均有不同程度降低,8例淋巴结转移患者及4例骨转移患者转移灶均缩小,术前骨痛及排尿症状均有好转,且无一例出现尿潴留及便血等严重并发症。结论:~(125)I放射性籽源植入术并内分泌疗法对各期前列腺癌均有明显的治疗作用,是一种安全有效的前列腺癌综合治疗手段。
Objective: To evaluate the clinical efficacy of ~ (125) I radioactive seed implantation combined with endocrine therapy in the treatment of prostate cancer. Methods: Twenty-nine patients with prostate cancer were treated with intraoperative transrectal ultrasound guidance and treatment planning system software via perineal puncture with 125I radioactive seeds and surgical castration or drug castration. Results: After 6 months to 5 years of follow-up, 29 cases of patients with prostate volume and prostate specific antigen (PSA) were reduced to varying degrees, 8 cases of lymph node metastasis and 4 cases of bone metastases in patients with metastases were reduced, preoperative bone Pain and urination symptoms have improved, and no case of urinary retention and blood in the stool and other serious complications. Conclusion: Radioactive seed implantation and endocrine therapy with ~ (125) I have obvious curative effect on all stages of prostate cancer, which is a safe and effective method for comprehensive treatment of prostate cancer.