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目的探讨研究饮食运动综合矫治对肥胖更年期妇女血浆胰岛素的影响。方法选择2010年1月-2011年1月在本院健康体检中心体检的42例肥胖更年期妇女作为研究对象,对研究对象进行定期健康教育,同时对其进行为期1个月的饮食运动综合矫治。分别在矫治前、矫治后检测血脂水平、体脂比、胰岛素抵抗指数、血浆胰岛素及C肽水平。结果矫治1个月后,研究对象总胆固醇、甘油三酯、低密度脂蛋白水平以及体脂比较矫治前显著降低,而高密度脂蛋白水平显著升高,差异均有统计学意义(P<0.05);研究对象胰岛素抵抗指数、血浆胰岛素及C肽水平较矫治前明显降低,差异均有统计学意义(P<0.05)。结论对肥胖更年期妇女进行饮食运动综合矫治可以明显改善血脂水平,降低脂肪百分比,同时能改善胰岛素抵抗并降低血浆胰岛素水平,从而能有效预防2型糖尿病的发生。
Objective To investigate the effects of dietary exercise on plasma insulin in obese menopause women. Methods Forty-two obese menopausal women undergoing physical examination in our hospital from January 2010 to January 2011 were enrolled in this study. Periodic health education was conducted on the subjects and their diet was treated for one month. Blood lipids, body fat ratio, insulin resistance index, plasma insulin and C-peptide levels were measured before treatment and after treatment. Results After correction for 1 month, the levels of total cholesterol, triglyceride, low density lipoprotein and body fat in the study group were significantly lower than those before treatment, while the levels of HDL were significantly increased (P <0.05 ); Insulin resistance index, plasma insulin and C-peptide levels in the study group were significantly lower than those before the treatment, the differences were statistically significant (P <0.05). Conclusions Dietary exercise regimen in obese menopausal women can significantly improve blood lipid levels, reduce fat percentage, improve insulin resistance and reduce plasma insulin levels, which can effectively prevent type 2 diabetes.