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目的观察雾化吸入与静脉滴注盐酸氨溴索注射液治疗新生儿肺炎的临床效果。方法选取医院收治的新生儿肺炎患儿30例为研究对象,随机分为对照组和观察组,每组15例。对照组采用盐酸氨溴索注射液静脉滴注治疗,观察组采用雾化吸入联合盐酸氨溴索注射液静脉滴注治疗。观察2组各时间段动脉血气指数、不良症状消失时间及临床总有效率。结果观察组症状及体征消失时间均短于对照组(P<0.05);治疗后,观察组12 h、24 h动脉血气指数均优于对照组(P<0.05);观察组总有效率为93.33%,高于对照组的73.33%(P<0.05)。结论雾化吸入联合盐酸氨溴索注射液静脉滴注治疗新生儿肺炎的治疗效果显著,值得临床推广应用。
Objective To observe the clinical effect of inhalation and intravenous infusion of ambroxol hydrochloride in the treatment of neonatal pneumonia. Methods Thirty children with neonatal pneumonia admitted to hospital were selected as study subjects and randomly divided into control group and observation group with 15 cases in each group. The control group was treated with ambroxol hydrochloride injection by intravenous drip, while the observation group was treated by atomization inhalation with ambroxol hydrochloride injection by intravenous drip. The arterial blood gas index, the disappearance time of adverse symptoms and the total clinical effective rate of the two groups were observed. Results The symptoms and signs disappeared in the observation group were shorter than those in the control group (P <0.05). After treatment, the arterial blood gas indexes in the observation group at 12 and 24 h were better than those in the control group (P <0.05). The total effective rate in the observation group was 93.33 %, Higher than the control group 73.33% (P <0.05). Conclusion The combination of nebulized inhalation and ambroxol hydrochloride injection for the treatment of neonatal pneumonia is effective and worthy of clinical application.