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选用3～10岁的小儿外科患者(ASAⅠ—Ⅱ)30例研究布比卡因硬膜外麻醉对维库溴铵的肌松作用(NMB)强度和时间的影响。术前口服咪唑安定0.5mg·kg~(-1)(最多15mg)。其中15例除全麻外合用腰部硬膜外阻滞,药物是0.5％布比卡因2.5mg·kg~(-1)。全麻诱导和维持采用N_2O:O_2(2:1),异丙酚和阿芬太尼。拇指内收肌连结EMG,每20s使用四个成串刺激来监测NMB。硬膜外注入布比卡因(平均血药农度0.86μg
Thirty patients aged 3 to 10 years with pediatric surgery (ASAⅠ-Ⅱ) were selected to study the effect of bupivacaine epidural anesthesia on the intensity and time of muscle relaxant (NMB) of vecuronium. Preoperative oral midazolam 0.5mg · kg -1 (up to 15mg). Among them, 15 cases combined with general anesthesia combined with lumbar epidural block, the drug is 0.5% bupivacaine 2.5mg · kg ~ (-1). Induction and maintenance of general anesthesia with N 2 O: O 2 (2: 1), propofol and alfentanil. The thumb adducts the muscle to the EMG and monitors the NMB every four seconds using a series of four stimuli. Bupivacaine was injected epidurally (mean serum creatinine 0.86 μg