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目的观察大肠癌术后复发患者血清ICAM-1水平的变化,探讨其临床意义。方法用ELISA法测定19例大肠癌术后复发患者和25例大肠癌根术后健康患者血清ICAM-1水平。结果大肠癌术后复发患者血清ICAM-1水平明显高于正常对照组。结论血清ICAM-1水平与大肠癌术后复发有关,临床中ICAM-1水平可作为预测大肠癌复发与否的有效指标之一。
Objective To observe the change of serum level of ICAM-1 in patients with recurrent colorectal cancer and to explore its clinical significance. Methods Serum ICAM-1 levels were measured by ELISA in 19 patients with postoperative recurrence of colorectal cancer and 25 patients with postoperative colon cancer. Results The serum level of ICAM-1 in patients with recurrent colorectal cancer was significantly higher than that in the normal control group. Conclusion The serum level of ICAM-1 correlates with the recurrence of colorectal cancer. The level of ICAM-1 in clinic can be used as one of the effective indexes to predict the recurrence of colorectal cancer.