酮康唑是一种新的口服咪唑类药物,具有广谱抗真菌作用.已用于多种人的真菌病获良好效果,包括浅部皮肤真菌病、慢性皮肤粘膜念珠菌病,副球孢子菌病、组织胞浆菌病和球孢子菌病.其作用机理推测为通过各种生化机制而导致真菌结构的最终死亡,主要是细胞壁上麦角甾醇的合成受干扰,亦 Ketoconazole is a new oral imidazole drug with a broad spectrum of antifungal activity that has been shown to be effective in a variety of human fungal diseases including superficial dermatophytosis, chronic cutaneous mucocutaneous candidiasis, Mycosis, histoplasmosis and coccidioidomycosis.The mechanism of action is presumed to result in the ultimate death of the fungal structure through various biochemical mechanisms, mainly interference of the synthesis of ergosterol on the cell wall