肉样瘤病常可累及肝脏,由多发性肝肉芽肿组成而在临床上却无明显的肝病症状。表现为肝细胞衰竭和门脉高压等严重肝病者罕见。但是,另一罕见类型为慢性肝内胆汁郁积,与原发性胆汁性肝硬变很酷似。本文报道2例由慢性肉样瘤病引起慢性肝内胆汁郁积,是经Kveim-Siltzbach皮肤试验活检组织检查和血清血管 Sarcoidosis often can affect the liver, composed of multiple hepatic granulomas but clinically no obvious symptoms of liver disease. Performance of liver failure and portal hypertension and other severe liver disease are rare. However, another rare type of chronic intrahepatic cholestasis resembles primary biliary cirrhosis. This article reports two cases of chronic intramedullary sarcoidosis caused by chronic intrahepatic cholestasis by Kveim-Siltzbach skin test biopsy tissue and blood vessels