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噻氯匹啶 (ｔｉｃｌｏｐｉｄｉｎｅ,ＴＩＣ)自 1974年被发现以来 ,作为一种新型抗血小板药物 ,其作用机制逐渐明了[1～ 4 ] 。在脑血管疾病中的作用已被评定 ,国外大宗临床随访研究发现 ,ＴＩＣ在预防缺血性脑血管病 (ＩＣＶＤ)的发生上 ,效果明显优于阿司匹林 (ＡＳＡ) [5～ 9
Ticlopidine (TIC) since its discovery in 1974, as a new anti-platelet drugs, the mechanism of action gradually became clear [1 ~ 4]. The role of TIC in cerebrovascular disease has been assessed. A large number of clinical follow-up studies abroad have found that TIC is superior to aspirin (ASA) in preventing ischemic cerebrovascular disease (ICVD) [5-9