目前,临床上骨质疏松的早期特异性生化诊断指标不多。笔者测定23例骨质疏松症患者血清中Ⅰ型胶原羧基端肽(ICTP)的浓度变化,比较了与骨密度值的关系,探讨在骨质疏松症早期诊断中的意义。一、资料与方法1.临床资料。①非骨质疏松组:本院骨伤科门诊无骨质疏松表现的病人25例,男7例,女18例,年龄31～80岁,平均52.3岁,骨密度正常。②骨质疏松组:本院门诊及住院的骨质 At present, there are not many indicators of early specific biochemical diagnosis of osteoporosis in clinic. The authors measured 23 patients with osteoporosis in serum type Ⅰ collagen carboxyterminal peptide (ICTP) concentration changes, compared with the relationship between the value of bone mineral density, explore the significance of early diagnosis of osteoporosis. First, data and methods 1. Clinical data. ① non-osteoporosis group: Our hospital orthopedic outpatient osteoporosis performance of 25 patients, 7 males and 18 females, aged 31 to 80 years, mean 52.3 years old, normal bone mineral density. ② osteoporosis group: hospital outpatient and hospitalized bone