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洪水泛滥,极易造成血吸虫病流行,目前防治血吸虫病的首选药物是吡喹酮。吡喹酮为新型广谱抗寄生虫药,对各种血吸虫病都有显著疗效。国外于70年代首先合成,我国在80年代研制成功,现为国家基本药物,被收入中、美、日等国药典。吡喹酮治疗血吸虫病的特点是:剂量小(约为一般药物剂量的1/10)、疗程短(从一般药物的20天或10天缩短为1~2天)、疗效好(一般患者治疗半年后,粪检虫卵转阴率为97.7%~99.4%)、代谢快、不良反应轻。
Flood flooding, can easily cause schistosomiasis epidemic, the current drug of choice prevention and treatment of schistosomiasis is praziquantel. Praziquantel is a new broad-spectrum antiparasitic drug with a significant effect on various schistosomiasis. Abroad was first synthesized in the 1970s. Our country was successfully developed in the 1980s. Now it is a national essential drug, and has been included in the pharmacopoeias of China, the United States, Japan and other countries. Praziquantel treatment of schistosomiasis is characterized by: small dose (about the general drug dose of 1/10), short course of treatment (from the general drug 20 days or 10 days shortened to 1 to 2 days), good effect (general patient treatment Half a year later, the fecal dropworm negative conversion rate of 97.7% to 99.4%), fast metabolism, mild adverse reactions.