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浸润和转移是恶性肿瘤细胞基本特征。从临床上看。大部份肿瘤病人不是死于原发瘤,而是死于癌瘤的浸润生长和转移。因此,癌细胞浸润生长的特性是一个主要的研究课题。关于癌细胞浸润生长方式和性质,据国内外文献报导,仍没有搞清楚。本实验的目的着重观察人体肺癌细胞在人肺组织中浸润生长的方式和其形态表现特点,为进一步了解肺癌细胞如何危害人体健康,提供初步形态学理论基础。材料和方法实验利用肺组织结构发育基本完善的人胎儿肺组织(七个月胎儿肺),无菌操作,切成2mm厚度长条器官小块作为器官培养底物。再将人体肺腺癌细胞株
Infiltration and metastasis are the basic features of malignant cells. From a clinical point of view. Most cancer patients do not die from primary tumors but die from infiltration, growth, and metastasis of cancerous tumors. Therefore, the characteristic of invasive growth of cancer cells is a major research topic. With regard to the manner and nature of the infiltration of cancer cells, it has not been clarified according to domestic and foreign literature reports. The purpose of this experiment is to observe the way in which human lung cancer cells infiltrate and grow in human lung tissue and its morphological characteristics, in order to further understand how lung cancer cells harm human health, provide a preliminary morphological theoretical basis. Materials and Methods Experiments were performed using human fetal lung tissue (seven-month fetal lung) with well-developed lung tissue structure. Aseptically, 2 mm thick long organ pieces were used as organ culture substrates. Human lung adenocarcinoma cell line