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脂肪栓塞综合征(FES)为长骨骨折后成人呼吸困难综合征(ARDS)的一种变异型。据认为其原因是由栓塞的骨髓脂肪作用于肺毛细血管,血小板以及循环内的游离脂肪酸通过复杂的相互作用引起的,最终导致肺毛细血管漏出,引起出血性间质性肺炎。虽然实验证实所有这种骨折后均可发生骨髓脂肪栓塞,但在长骨骨折后出现呼吸衰竭,发热,瘀点,意识改变等典型的综合征仍属少见。
Fat embolism syndrome (FES) is a variant of adult respiratory distress syndrome (ARDS) after a long bone fracture. It is thought that the reason is that embolized marrow fat acts on the pulmonary capillaries, and platelets and free fatty acids in the circulation are caused by complicated interactions, eventually leading to leakage of pulmonary capillaries and causing hemorrhagic interstitial pneumonia. Although experiments have shown that all of these fractures can occur after the fatal embolism of the marrow, but after the long bone fracture respiratory failure, fever, petechia, changes in consciousness and other typical syndrome is still rare.