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用胶体金法对204例慢性无症状HBV感染者肝组织内病毒抗原进行了免疫组织化学研究.慢性无症状肝炎(AsH)与慢性无症状携带者(AsC)的肝组织病变不同,但病毒抗原的检出率却无显著差别;AsH与慢性乙型肝炎(CHB)的肝组织病变近似,但AsH病毒抗原的检出率却显著高于CHB.这可能与慢性无症状HBV感染者对病毒抗原在肝组织内的免疫应答低下有关,而肝组织病变可能是对长期感染的组织反应的累积.
Colloidal gold method was used to study the immunohistochemistry of viral antigens in 204 patients with chronic asymptomatic HBV infection.Chronic asymptomatic hepatitis (AsH) and chronic asymptomatic carriers (AsC) have different pathological changes of liver tissue, but viral antigens The detection rate of AsH was similar to that of chronic hepatitis B (CHB), but the detection rate of AsH virus antigen was significantly higher than that of CHB.This may be related to the relationship between chronic asymptomatic HBV infection and viral antigen The low immune response in liver tissue is related to liver tissue lesions that may be an accumulation of tissue responses to long-term infections.