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神经特异性烯醇酶(NSE)是糖代谢中烯醇酶的同功酶,即γ-烯醇酶。本文研究了接受治疗的小细胞肺癌(SCLC)患者血清 NSE(s-NSE)的测定与其疗效、预后、复发之间的关系。对象和方法对象为1984年10月至1987年5月住院的86例 SCLC 患者,其中男67、女19例,平均年龄67.1岁,均经细胞学或组织学确诊。依据 ECOG 分类:0~Ⅰ者43例,Ⅱ~Ⅲ者38例,Ⅳ者5例,肺癌病灶局限者40例,病变广泛者46例。本组大多数病
Neuron-specific enolase (NSE) is an isoenzyme of enolase in glycometabolism, namely γ-enolase. This study investigated the relationship between serum NSE (s-NSE) and the outcome, prognosis, and recurrence of patients with small cell lung cancer (SCLC). Subjects and Methods Subjects Eighty-six patients with SCLC who were hospitalized from October 1984 to May 1987, including 67 males and 19 females, with an average age of 67.1 years, were confirmed by cytology or histology. According to the ECOG classification, there were 43 cases of 0-I, 38 cases of II-III, 5 cases of IV, 40 cases of lung cancer lesions, and 46 cases of extensive lesions. Most diseases in this group