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目的观察复方丹参滴丸联合氨氯地平片治疗活动平板试验阳性高血压患者的临床疗效。方法将146例活动平板试验阳性高血压患者随机分为两组;对照组66例给予氨氯地平治疗,观察组80例给予复方丹参滴丸联合氨氯地平片治疗,疗程4周。观察两组心电图疗效、治疗前后收缩压峰值及心电图活动平板试验指标变化情况。结果 1观察组心电图总有效率为96.25%,对照组为83.33%;两组心电图疗效比较有显著性差异(P<0.05)。2治疗后两组收缩压峰值均较治疗前降低(P<0.05),且观察组明显低于对照组(P<0.05)。3治疗后两组活动平板试验各指标均较治疗前明显改善(P<0.05),且观察组改善情况优于对照组(P<0.05)。结论复方丹参滴丸联合氨氯地平片治疗活动平板试验阳性高血压疗效确切,且具有心脏保护作用。
Objective To observe the clinical efficacy of compound Danshen dripping pills combined with amlodipine tablets in the treatment of active hypertensive patients. Methods One hundred and sixty-six patients with active hypertension were randomly divided into two groups. Sixty-six patients in the control group were given amlodipine. Eighty patients in the observation group were given Danshen dropping pills combined with amlodipine for 4 weeks. Electrocardiogram curative effect of two groups were observed, before and after treatment, peak systolic blood pressure and electrocardiogram activity plate test index changes. Results 1 The total effective rate of electrocardiogram in observation group was 96.25%, while that of control group was 83.33%. There was significant difference between the two groups in the curative effect of electrocardiogram (P <0.05). After treatment, the peak systolic blood pressure of both groups was lower than that before treatment (P <0.05), and the observation group was significantly lower than that of the control group (P <0.05). After treatment, the indexes of active treadmill test in both groups were significantly improved (P <0.05), and the improvement in the observation group was better than that in the control group (P <0.05). Conclusion Compound Danshen dripping pills combined with amlodipine tablets for the treatment of active test positive for platelet positive effect, and has a cardioprotective effect.