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目的:为观察豚鼠潜水60米减压后对DPOAE、皮层诱发电位及中耳形态学的影响.方法:杂色健康豚鼠8只,加压前及减压后进行DPOAE及皮层诱发电位测试及颞骨切片,光镜观察.结果:正常豚鼠潜水减压后DPOAE幅值强度及皮层诱发电位有不同程度的改变与进舱前比有差异及显著差异性,内耳形态学变化重者DPOAE值下降亦明显.结论:鼓膜及中耳的阻抗发生变化,以致DPOAE值下降、皮层诱发电位阈值升高,与形态学的改变有相关性,说明中耳质量及劲度声抗的改变可以影响DPOAE幅值,DPOAE可对中耳功能进行评估.
OBJECTIVE: To observe the effects of 60m decompression on guinea pigs submerged pressure on the DPOAE, cortical evoked potentials and middle ear morphology.Methods: Eight healthy and guinea pigs with guinea pigs were subjected to DPOAE and cortical evoked potentials before and after decompression, Slice and light microscopy.Results: The DPOAE amplitude and cortical evoked potentials in normal guinea pigs had different degrees of difference and significant differences before and after diving decompression, and the DPOAE value decreased significantly in severe morphological changes of the inner ear .Conclusion: The changes of impedance in the tympanic membrane and the middle ear caused the decrease of DPOAE and the increase of cortical evoked potentials, which was correlated with the morphological changes, indicating that the changes of middle ear mass and stiffness sound impedance could affect the amplitude of DPOAE, DPOAE can evaluate middle ear function.