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患原发或转移性肝肿瘤的病人,诊断后的平均生存期为6个月,中位生存期为1.5个月。通过静脉或动脉给予化疗药物效果不佳。局部放疗一般不适用。为提高疗效,作者用~(?)镱-微球经肝动脉注入治疗15例肝脏恶性肿瘤。~(?)镱是纯β辐射体,半衰期64.2小时,β粒子平均能量0.93Mev,在组织内有效辐射半径为2.5mm。~(?)”镱牢固地结合在直径为15±5um 的树脂微球上。经皮由腹动脉插入导管,进八肝动脉后注入这种微球的悬浮液。~(?)镱的用量根据患者肝脏的重量计算。
Patients with primary or metastatic liver tumors had a median survival of 6 months after diagnosis and a median survival of 1.5 months. The administration of chemotherapeutic drugs by vein or artery is not effective. Local radiotherapy generally does not apply. To improve the efficacy, the authors used hepatic arterial infusion of ~ (?) 镱-microspheres to treat 15 cases of hepatic malignancies. The ~(?) 镱 is a pure beta radiator with a half-life of 64.2 hours. The average energy of the beta particles is 0.93 MeV and the effective radiation radius in the tissue is 2.5 mm. The ~(?)" plaque is firmly attached to a resin microsphere of 15 ± 5 μm in diameter. The catheter is inserted percutaneously from the abdominal artery into the suspension of the microspheres into the eight hepatic arteries. Calculated based on the weight of the patient’s liver.