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检测乳腺癌中雌、孕激素受体(ER、PR)对是否选择内分泌治疗十分重要,同时检测P53,于乳腺癌预后及是否存在淋巴结转移的高危性判断可提供一个客观的指标。本组实验,在于探讨ER、PR、P53与临床病理的相关关系。 1 材料和方法 1.1 标本来源:取材于我院1990～1992年术后乳腺癌120例,同时有淋巴结癌转移40例,无转移淋巴结40例,用组织石蜡切片。肿瘤大小为1cm～8cm不等,<2.5cm的52例,>2.5cm的68例。发病年龄12岁～59岁。
Detection of estrogen and progesterone receptor (ER, PR) in breast cancer is very important for the choice of endocrine therapy. Simultaneous detection of P53 may provide an objective indicator for the prognosis of breast cancer and the high risk of lymph node metastasis. This group of experiments, is to explore the relationship between ER, PR, P53 and clinical pathology. 1 Materials and Methods 1.1 Specimen Source: Based on our hospital from 1990 to 1992, 120 cases of postoperative breast cancer, at the same time there are 40 cases of lymph node metastasis, no transfer of lymph nodes in 40 cases, with tissue paraffin sections. Tumor sizes ranged from 1 cm to 8 cm, with 52 cases of <2.5 cm and 68 cases of> 2.5 cm. The age of onset of 12 years old to 59 years old.