论文部分内容阅读
植物雌激素α-玉米赤霉醇是一种广泛存在于植物中的非甾体类化合物,生物学活性类似于雌激素,是一种选择性雌激素受体调质。α-玉米赤霉醇通过调节血脂代谢、抑制血管平滑肌的增殖迁移、调节血管活性因子的合成和释放、抗氧化损伤等发挥其广泛的心血管保护作用,并且乳腺癌、子宫内膜癌的发病风险并无明显增加,为心血管疾病的预防和治疗提供了新的思路,很有希望成为雌激素的替代药物。
The phytoestrogenic α-zearalanol is a non-steroidal compound widely found in plants. Its biological activity is similar to that of estrogen. It is a selective estrogen receptor modulator. Alpha-zearalan exerts its extensive cardiovascular protection by regulating blood lipid metabolism, inhibiting the proliferation and migration of vascular smooth muscle, regulating the synthesis and release of vasoactive factors, and preventing oxidative damage, etc., and the incidence of breast cancer and endometrial cancer There is no significant increase in risk, providing new ideas for the prevention and treatment of cardiovascular disease, and it is hopeful to become an alternative medicine for estrogen.