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胸腺素(Thymosin)是一种活性多肽和蛋白质。1966年 Goldstein 等已经提取了小牛胸腺素,1975年用于临床治疗自身免疫性疾病、免疫缺陷病等取得了良好的效果,证明胸腺素能使淋巴细胞分化成为有免疫功能的 T 细胞,因而具有调节细胞免疫的功能。1977年南京大学生物系和泰州生化制药厂参照国外有关文献,结合我国制药工业的情况,提纯了一种猪胸腺素(简称 PTF_5),实验证明安全无毒。1979年我们用来治疗口疮和白塞氏综合征,今将南京市口腔医院与南大医院50例(附对照组
Thymosin is an active polypeptide and protein. In 1966, Goldstein et al. Had extracted calf thymosin and achieved good results in the clinical treatment of autoimmune diseases, immunodeficiency diseases and the like in 1975, demonstrating that thymosin can differentiate lymphocytes into immunocompetent T cells and thus Has the function of regulating cellular immunity. In 1977, the Department of Biology, Nanjing University and Taizhou Biochemical Pharmaceutical Factory, referring to relevant foreign literature, combined with the situation of China's pharmaceutical industry, purified a kind of porcine thymosin (referred to as PTF_5), the experiment proved safe and non-toxic. In 1979 we used to treat aphthous and Behcet's syndrome, now Nanjing Stomatological Hospital and South Hospital 50 cases (with the control group