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目的观察空腹血糖、胰岛素水平及肥胖对老年原发性高血压左室舒张功能的影响。方法检测40例健康老年人,43例老年原发性高血压及36例原发性高血压合并肥胖者的血糖、胰岛素水平及超声心动图。结果原发性高血压组等容舒张时间明显延长,E/A比值明显下降,合并肥胖者尤为明显。结论肥胖、糖耐量异常及高胰岛素血症,胰岛素抵抗加重老年原发性高血压患者左室舒张功能障碍。
Objective To observe the effects of fasting blood glucose, insulin and obesity on left ventricular diastolic function in elderly patients with essential hypertension. Methods Blood glucose, insulin and echocardiography were measured in 40 healthy elderly, 43 elderly patients with essential hypertension and 36 patients with essential hypertension complicated with obesity. Results In the essential hypertension group, the isovolumic relaxation time was significantly prolonged, the ratio of E / A decreased significantly, especially in those with obesity. Conclusion Obesity, impaired glucose tolerance and hyperinsulinemia, insulin resistance aggravate left ventricular diastolic dysfunction in elderly patients with essential hypertension.