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目的了解男男同性恋者(MSM)中人类免疫缺陷病毒(HIV)感染者梅毒快速血浆反应素环状卡片试验(RPR)生物学假阳性反应(BFP)情况。方法对我院MSM人群筛查队列进行RPR试验、梅毒螺旋体明胶凝集试验(TPPA)试验和HIV抗体初筛,比较梅毒RPR生物学假阳性(RPR-BFP)发生情况。结果共10 000例MSM,HIV抗体阳性者中,RPR-BFP 0.15%(3/1 989);HIV抗体阴性者中,RPR-BFP0.27%(22/8 011)。该两组人群RPR试验假阳性率差异无统计学意义(P>0.05)。结论 HIV感染没有增加梅毒RPR生物学假阳性反应。
Objective To investigate the biological false positive reaction (BFP) of syphilis in patients with human immunodeficiency virus (HIV) infection in male homosexual men (MSM). Methods RPR test, TPPA test and HIV antibody screening were performed on the screening cohort of MSM in our hospital. The incidence of syphilis RPR-BFP was compared. RESULTS: A total of 10 000 MSM were identified. RPR-BFP was 0.15% (3/1 989) of HIV-positive individuals and 0.27% (22/8 011) of RPR-BFP in HIV-negative individuals. There was no significant difference in the RPR test false positive rate between the two groups (P> 0.05). Conclusion HIV infection did not increase the false positive of RPR in syphilis.