CD34是一种阶段特异性的白细胞分化抗原,选择性地表达于早期造血干/祖细胞表面。近年研究发现CD34阳性(CD34+)细胞在哮喘患者骨髓、外周血及肺组织局部明显增多,它可能参与哮喘时特异性嗜酸粒细胞性气道炎症的形成。深入研究CD34+细胞在哮喘中的作用有助于阐明该疾病的发生机制,并为其治疗拓展新的思路。 CD34 is a stage-specific leukocyte differentiation antigen that is selectively expressed on the surface of early hematopoietic stem / progenitor cells. In recent years, studies have found that CD34 positive cells (CD34 +) significantly increased in the bone marrow, peripheral blood and lung tissue of asthmatic patients, which may be involved in the formation of specific eosinophilic airway inflammation during asthma. In-depth study of the role of CD34 + cells in asthma help to clarify the pathogenesis of the disease and to develop new ideas for its treatment.