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目的:探讨补肾健脾方对乳腺癌CE(A)T化疗所致白细胞减少症的影响,寻找改善白细胞减少症更稳定、安全而有效的方法。方法:采用随机对照研究方式,将30例患者随机分为2组,每组各15例。治疗组:CE(A)T化疗+中药治疗±欣粒生;对照组:CE(A)T化疗±欣粒生。两组病人化疗各疗程的第7天、第14天及第20天检测白细胞计数。1个化疗周期(即21天)为1个疗程。结果:与对照组相比,治疗组能够提高患者白细胞计数,有效缓解CE(A)T化疗相关白细胞减少症,降低发热机会及减少rhG-CSF应用,具有统计学差异。结论:补肾健脾方是治疗乳腺癌CE(A)T化疗所致白细胞减少症有效方法。
Objective: To investigate the effect of Bushen Jianpi Fang on leucopenia induced by chemotherapy of breast cancer CE (A) T, and find out a more stable, safe and effective method to improve leucopenia. Methods: A randomized controlled study, 30 patients were randomly divided into two groups, each group of 15 cases. Treatment group: CE (A) T chemotherapy + Chinese medicine treatment ± Xin tablets; control group: CE (A) T chemotherapy ± Xin tablets students. The two groups of patients with chemotherapy treatment of the first 7 days, 14 days and 20 days detection of white blood cell count. A chemotherapy cycle (ie 21 days) for a course of treatment. Results: Compared with the control group, the treatment group can improve the patients’ white blood cell count, relieve the chemotherapy-related leucopenia of CE (A) T, reduce the chance of fever and reduce the application of rhG-CSF, with statistical difference. Conclusion: Bushen Jianpi Fang is an effective method for the treatment of leucopenia induced by CE (A) T in breast cancer.