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目的观察中药保留灌肠联合序贯腹膜透析治疗儿童急性肾衰竭的临床疗效。方法将22例确诊为急性肾衰竭的患儿随机分为治疗组和对照组各11例,对照组予药物及对症治疗;治疗组在中药保留灌肠3 d后,予序贯腹膜透析治疗。结果治疗组总有效率为90.91%,对照组为81.82%。2组总有效率比较差异有统计意义(P<0.05);治疗组尿量增多时间及血清肌酐(Scr)下降时间均短于对照组(P<0.05),症状缓解时间显著短于对照组(P<0.01)。结论中药保留灌肠联合序贯腹膜透析治疗儿童急性肾衰竭效果良好,可有效缩短病程,提高生存质量及抢救成功率,值得临床推广。
Objective To observe the clinical efficacy of traditional Chinese medicine retention enema combined with sequential peritoneal dialysis in children with acute renal failure. Methods Twenty-two children diagnosed with acute renal failure were randomly divided into treatment group (11 cases) and control group (11 cases). The control group was treated with drugs and symptomatic treatment. The treatment group was treated with sequential peritoneal dialysis after 3 days of retention of enema. Results The total effective rate was 90.91% in the treatment group and 81.82% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). The time of excretion of urine and the decline of serum creatinine (Scr) in the treatment group were shorter than those in the control group (P <0.05), and the symptom relief time was significantly shorter than that in the control group P <0.01). Conclusion Traditional Chinese medicine enema with sequential sequential peritoneal dialysis treatment of acute renal failure in children with good results, which can effectively shorten the course of disease and improve the quality of life and rescue success rate, worthy of clinical promotion.