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糖尿病性视网膜病变(以下简称DR),是糖尿病患者常见的并发症,也是中国和西方国家中老年人常见的后天性致盲眼病。糖尿病患者引起视网膜微血管的功能性改变表现为:①微血管囊样扩张;②微血栓形成;③毛细血管壁细胞丧失;④基底膜增厚。随着近年来激光电凝等方法的改进,DR致盲危险性显著降低。探讨DR的发病机制对预防和早期治疗DR有重要意义。现将其发病机制综述如下。
Diabetic retinopathy (hereinafter referred to as DR), is a common complication of diabetes patients, but also in China and Western countries common in the elderly acquired acquired blind eye disease. Diabetic patients caused by the functional changes of the retinal capillaries manifested as: ① microvascular cystic dilatation; ② micro-thrombosis; ③ loss of capillary wall cells; ④ basement membrane thickening. With the improvement of laser coagulation and other methods in recent years, the risk of DR blinding is significantly reduced. To explore the pathogenesis of DR is of great importance in the prevention and early treatment of DR. The pathogenesis is summarized below.