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成人Still’s病(Adult Onset Still’s Disease,AOSD)是病因未明以高峰热、一过性多形性皮疹、关节炎或关节痛为主要临床表现,并伴有周围血粒细胞增高,肝脾淋巴结肿大等系统受累的一种临床综合征。由于临床表现类似败血症,而血培养又始终阴性,故称“亚败血症”,因有一过性皮疹和关节症状等表现又称“变态反应性败血症”。1985年我国第二届风湿病学术会议建议摒弃亚急性败血症和变态反应性败血症等名称,统一用成人Still’s病命名。因本病临床表现复杂多变,极易与其它疾病混淆,误诊甚多,所以应该认真研究,提高认识水平。本文作者在治疗5例成人Still’s病的基础上结合有关文献加以综述。
Adult Still’s disease (Adult Onset Still’s Disease, AOSD) is the etiology of unknown peak fever, transient rash, arthritis or joint pain as the main clinical manifestations, accompanied by increased peripheral blood neutrophils, hepatosplenomegaly Other clinical involvement of a clinical syndrome. Because of clinical manifestations similar to sepsis, and blood culture has always been negative, so called “sub-sepsis”, due to a transient rash and joint symptoms, also known as “allergic sepsis.” In 1985 China’s second session of the rheumatology conference proposed to abandon the name of subacute sepsis and allergic sepsis, unified with the name of Still Still’s disease. Clinical manifestations of the disease because of the complex and volatile, easily confused with other diseases, many misdiagnosed, it should be carefully studied to raise awareness. The author of the article in the treatment of 5 cases of adult Still’s disease based on the literature to be reviewed.