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[目的]在补土理论指导下,观察中医药对克罗恩病(CD)维持缓解的疗效及生活质量影响。[方法]选取符合纳入标准的29例CD缓解期患者,使用自身对照观察方法,进行为期6个月干预,观察简化CDAI、SF-36、IBDQ在干预前后的变化。[结果]CD患者使用补土方案3个月后与6个月后的简化CDAI评分均较使用前下降,SF-36与IBDQ较使用前提高,差异均有统计学意义(P<0.05)。[结论]补土方案对于CD可以达到有效维持缓解,并可改善生存质量。
[Objective] Under the guidance of soil remediation theory, observe the curative effect and quality of life of traditional Chinese medicine to maintain the relief of Crohn’s disease (CD). [Methods] Twenty-nine patients with CD remission who met the inclusion criteria were selected and their self-control observation method was used for six-month intervention to observe the changes of simplified CDAI, SF-36 and IBDQ before and after intervention. [Results] The simplified CDAI scores of patients with CD at 3 months and 6 months after use of earth-filling regimen decreased compared with those before use, and the scores of SF-36 and IBDQ were higher than those before use. The differences were statistically significant (P <0.05). [Conclusion] The soil remediation program can effectively maintain the relief for CD and improve the quality of life.