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目的 探讨6项放免指标联合诊断原发性肝癌和胃肠癌术后的复发或转移。方法 对1993年以来住院的恶性肿瘤患者130例,其中胃肠癌术后96例,原发性肝癌34例。分为稳定组和不稳定组,放免测定其血清中CA_(-50),CA_(-199),CEA,AFP,SF和β_2-M。结果 3项指标同时阳性,有助于原发性肝癌的诊断,亦有助于胃肠癌术后复发或转移的诊断(P<0.01)。在CA_(-50),A_(-199)及CEA中,出现1～2项阳性者,应高度警惕胃肠癌术后复发或转移。结论 肿瘤标志物CA_(-50),CA_(-199),CEA、AFP、SF和β_2-M等6项,可用于联合诊断原发性肝癌和胃肠癌术后复发或转移,也可用于判断预后。
Objective To investigate the recurrence or metastasis of primary liver cancer and gastrointestinal cancer after 6-item radioimmunoassay. Methods There were 130 patients with malignant tumors hospitalized since 1993, including 96 patients with gastrointestinal cancer and 34 patients with primary liver cancer. They were divided into stable group and unstable group. They were assayed by radioimmunoassay for serum CA_ (-50), CA_ (-199), CEA, AFP, SF and β_2-M. Results The three indicators were positive at the same time, which contributes to the diagnosis of primary liver cancer and also helps to diagnose the recurrence or metastasis of gastrointestinal cancer (P<0.01). In CA_(-50), A_(-199) and CEA, 1 to 2 positive cases should be highly alert to recurrence or metastasis of gastrointestinal cancer. Conclusion The tumor markers CA_(-50), CA_(-199), CEA, AFP, SF and β_2-M can be used for the combined diagnosis of recurrence or metastasis of primary liver cancer and gastrointestinal cancer. To determine the prognosis.