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采用宽带激光熔覆技术,通过在涂层中加入稀土氧化物Nd_2O_3来改善涂层显微组织、表面形貌和提高涂层生物活性、细胞相容性的方法,制备了一种梯度生物活性陶瓷涂层。利用金相分析、SEM分析手段对涂层显微组织、形貌进行了研究;通过模拟体液(SBF)浸泡实验考察了涂层活性;采用人成骨细胞与涂层材料共培养的方式,验证了细胞在涂层表面的粘附生长和定向分化能力。结果表明:涂层中添加Nd_2O_3时,涂层显微组织和表面形貌优于没有加入Nd_2O_3的涂层;加入Nd_2O_3的涂层表面生成的HA+β-TCP相多于没有添加Nd_2O_3的涂层,生物活性更好;添加Nd_2O_3的涂层具有更好的细胞相容性和细胞活性。
The broadband laser cladding technique was used to prepare a gradient bioactive ceramic by adding rare earth oxide Nd_2O_3 to the coating to improve the microstructure, surface morphology and bioactivity of the coating and cell compatibility. coating. The microstructure and morphology of the coating were studied by means of metallographic analysis and SEM analysis. The coating activity was investigated by immersing in simulated body fluid (SBF). The co-culture of human osteoblasts and coating material was used to verify Cell adhesion on the surface of the coating growth and directional differentiation. The results show that the microstructure and surface morphology of the coating are better than those without Nd_2O_3 coating when Nd_2O_3 is added into the coating. The HA + β-TCP phase is more formed on the surface of Nd_2O_3 coating than the coating without Nd_2O_3 , Biological activity better; Nd_2O_3 coating with better cell compatibility and cell activity.