目的探讨危重病患者继发深部真菌感染发病情况。方法回顾性分析近2年间47例危重病患者继发深部真菌感染的临床资料。结果病原菌以念珠菌为主(98%),其中白色念珠菌(72%);感染部位以泌尿道为(39%),其次为肺部(35%),且大多为两个及两个以上部位同时感染。结论危重病患者因注意控制真菌感染的高危因素,同时合理选用抗真菌药物。 Objective To investigate the incidence of secondary fungal infections in critically ill patients. Methods Retrospective analysis of 47 cases of critical illness in recent 2 years, the clinical data of deep fungal infection. Results The pathogen was Candida albicans (98%), Candida albicans (72%), Urinary tract was the infection site (39%), followed by the lung (35%), and most of them were two or more Parts of the same infection. Conclusion The critically ill patients should pay attention to the risk factors of fungal infection control, while rational use of antifungal drugs.