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To investigate the effects of low-dose carbon ion irradiation on reproductive system of male mice,the testes of outbred Kun-Ming strain mice were whole-body irradiated with 0,0.05,0.1,0.5 and 1.0 Gy carbon beams respectively. The beam energy of carbon particles was 80.55 MeV/u,corresponding to an average of 31.3 keV/μm. The DNA double-strand breaks(DNA DSBs)and oxidative stress parameters including malondialdehyde(MDA)content,superoxide dismutase(SOD)activity,and testis weight and sperm count at 12 h,21 and 35 d after irradiation in mouse testis were measured. At 12 h post-irradiation,a significant increase in DNA DSB level but no pronounced alterations in MDA content or SOD ac
To investigate the effects of low-dose carbon ion irradiation on reproductive system of male mice, the testes of outbred Kun-Ming strain mice were whole-body irradiated with 0, 0.05, 0.1, 0.5 and 1.0 Gy carbon beams respectively. The beam energy The DNA double-strand breaks (DNA DSBs) and oxidative stress parameters include malondialdehyde (MDA) content, superoxide dismutase (SOD) activity, and testis weight and sperm count at 12 h, 21 and 35 d after irradiation in mouse testis were measured. At 12 h post-irradiation, a significant increase in DNA DSB level but no pronounced alterations in MDA content or SOD ac