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乳腺癌是实体瘤中应用化疗最有效的肿瘤之一,化疗在整个治疗中占有重要地位。由于手术尽量去除了肿瘤负荷,残存的肿瘤细胞易被化学抗癌药物杀灭。已证实浸润型乳腺癌术后应用化学药物辅助治疗可以改善生存率。CAF方案为常用的术后辅助化疗方案,但阿霉素(ADM)由于较明显的心脏毒性等副作用使其临床应用受到限制,吡柔比星
Breast cancer is one of the most effective tumors in the application of chemotherapy in solid tumors, and chemotherapy plays an important role in the whole treatment. Due to surgery as much as possible to remove the tumor burden, the remaining tumor cells are easily killed by chemical anti-cancer drugs. Confirmed invasive breast cancer after chemotherapy with adjuvant chemotherapy can improve the survival rate. CAF regimen is commonly used postoperative adjuvant chemotherapy regimen, but doxorubicin (ADM) limits its clinical application due to its obvious side effects such as cardiotoxicity. Pirarubicin